English name: Costus Root
Use Part: root
Appearance: brown powder
Mesh size: 80 Mesh
Test Method: TLC
Effects on the respiratory system: guinea pig isolated tracheal and lung perfusion experiments have shown that wood extract, alcohol extract, volatile oil and total alkaloids can counteract the effects of histamine and acetylcholine on tracheal and bronchial caries. The lactones, such as total lactones, licolactones, dihydroxylactone and volatile oils, can resist bronchoconstriction caused by histamine, acetylcholine and barium chloride, among which dihydrowood The action of the lactone is stronger. Intraperitoneal administration has protective effects on inhaled lethal dose of histamine or acetylcholine aerosol guinea pigs, which can prolong the latency of asthma and reduce mortality. The above results indicate that the characteristics of bronchial smoothing are similar to those of papaverine. It is thought that direct action is caused by smooth muscle. The chest cannula was inserted into the pleural cavity of the anesthetized cat, and the bronchodilation reaction was observed by intravenous injection of Yunmu. However, the destruction of the animal brain and then the administration is ineffective, suggesting that its effect is related to the central nervous system inhibition. The aqueous extract, alcohol extract, volatile oil, volatile oil of lactone and total alkaloids have a certain inhibitory effect on the breathing of anesthetized dogs. Among them, the volatile oil has a strong effect, and the lactone components contained in the volatile oil have no significant effect on the respiration. Dog mechanical stimulation cough test proved that the volatiles in the volatiles and lactone volatile oil did not have antitussive effect.
Effects on the intestine: The wood perfume extract, volatile oil and total alkaloids have mild excitatory effects on the isolated small intestine of mice, and then the tonicity and rhythm are significantly reduced. It has an antagonistic effect on intestinal tendon caused by acetylcholine, histamine and barium chloride. The effect of low-dose decoction on the isolated small intestine has no regularity, and the large dose has an inhibitory effect. Volatile oil can also inhibit the movement of isolated rabbit small intestine, making its rhythm slow and irregular contraction. The volatiles of lactone volatile oil, total lactone, and woody lactone, dihydroxylactone and dihydroxylactone have stronger effects.
Cardiovascular effects: low concentrations of woody volatile oil and various lactone fractions isolated from volatile oil can inhibit the activity of guinea pig and rabbit isolated heart to varying degrees, and also inhibit the isolated frog heart.
Certificate of Analysis
100%through 80 mesh
Total of bacteria
Storage Store in cool & dry place. Do not freeze.
Keep away from strong light and heat.
Shelf life 2 years when properly stored
Costus root extract can be used to relieve pain by promoting the flow of qi, and to improve digestion by reinforcing the spleen function. Costus root extract helps relieve epigastric distension. Costus root extract is also used to treat the abdominal pain, diarrhea, and tenesmus by nourishing the spleen and removing stasis in stomach and intestines.
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